Expression of variants of CD44 molecules in polymorphic adenoma of salivary glands
- VernacularTitle:CD44不同变异体在涎腺多形性腺瘤中的表达及意义
- Author:
Fang LIU
;
Yu PAN
;
Junpeng LAI
;
Yingshi LIU
- Publication Type:Journal Article
- Keywords:
Salivary gland neoplasms;
Adenoma;
Pleomorphic;
Antigens,CD44
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(4):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of CD44v3 and CD44v6 in the polymorphic adenoma of salivary glands. Methods Using immunohistochemistry technology to detect the expression of CD44v3 and CD44v6 in 30 cases of polymorphic adenoma of salivary glands. Results The expression of CD44v3 was positive in 66.7 %cases within 30 paraffin-embedded sections, while CD44v6,86.7 % was positive. Conclusion The high expression of CD44v3 and CD44v6 maybe the reason of the low invasive ability and migration of polymorphic adenoma of salivary glands.
