Clinicopathological study of small cell carcinoma of the cervix
- VernacularTitle:宫颈小细胞癌的临床病理分析
- Author:
Yuan QU
- Publication Type:Journal Article
- Keywords:
Small cell carcinoma of cervix;
Immunohistochemistry;
Vascular endothelial growth factor
- From:
Journal of Medical Postgraduates
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical and pathological features of small cell carcinoma of cervix.(SCCC).Methods:Clinical data,pathological changes and immunohistochimical findings were reviewed in 7 cases of small cell cervical carcinoma(SCCC),and immunohistochemical staining was performed for VEGF in 4 cases of SCCC.Results:The average age was 37 years in 7 patients,and the main symtoms were vaginal bleeding.Under microscope,tumor cells showed oat or intermediate cell type,Three tumors were associated with other forms of carcinoma: squamous cell carcinoma,endometrial carcinoma,poor-differentiated adenocarcinoma.Immunohistochemical staining showed neuroendocrine differentiation and VEGF.Their FIGO staging was stage Ⅰ_b in 2 cases,stage Ⅱ in 2 cases,stage Ⅲ in 2 cases.In the 5 patients with follow-up data,4 were dead and 1 was in following up.Conclusion:Small cell carcinoma of the cervix has stated an extremely aggressive biological behavior with minimal survival chances and a rapid and fatal clinical course.
