Cholesteryl ester transfer protein gene variation relate to lipid parameters and cardiovascular risk
- VernacularTitle:胆固醇酯转运蛋白基因变异与血脂和动脉粥样硬化性心血管病的关系
- Author:
Junjun WANG
;
Chunni ZHANG
- Publication Type:Journal Article
- Keywords:
Cholesteryl ester transfer protein;
Genetics;
Lipid;
Atherosclerosis
- From:
Journal of Medical Postgraduates
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Cholesteryl ester transfer protein(CETP) plays an important role in the transfer and exchange of cholesteryl esters,phospholipid and triacyglycerols.It affects lipid composition,concentration,particle size and function of lipoproteins, partcipating in the development of atherosclerosis.The role of CETP in human atherosclerosis has not been fully elucidated.Gene variations of the CETP were associated with altered CETP plasma levels and activity,lipid metabolism disorder.The relationships between CETP gene variation,lipid parameters and cardiovascular risk was reviewed.
