Characterization and clinical significance of the Smith antigen
- VernacularTitle:Smith抗原的性质特征及临床意义
- Author:
Wenbing WU
;
Xiaopeng LAN
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus;
The Smith antigen;
Characterization;
Biological functions
- From:
Journal of Medical Postgraduates
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus(SLE) is an autoimmune disease characterized by the production of autoantibodies against a wide spectrum of nuclear, cytoplasmic,and cell membrane autoantigens.Among them,the anti-Smith antibodies are specific for SLE and thus have been included as a criteria for diagnosis.They are not only a diagnostic marker but also a reliable measure of disease activity in SLE,we intend to describe the biological functions and clinical significance of the Smith antigen and the detection of anti-Smith antibodies.
