The application of endothelial progenitor cells in glioma
- VernacularTitle:内皮祖细胞与胶质瘤关系的研究进展
- Author:
Junxia ZHANG
;
Yongping YOU
;
Zhen FU
- Publication Type:Journal Article
- Keywords:
Endothelial progenitor cell;
Glioma;
Homing;
Gene therapy
- From:
Journal of Medical Postgraduates
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Endothelial progenitor cells(EPC),which have the capacity to differentiate into mature endothelial cells,have been found to home to and incorporate into the angiogenic vasculature of growing tumors with high specificity once mobilized into the circulation.Yet the mechanism still remains unclear.EPC have potential as spatial-specific delivery vehicles.Thus,further studies on the mechanisms of tumor neovascularization and tumor therapy in glioma using genetically engineered EPC as angiogenesis-selective vectors will be of help to explore the potential in the basic and clinical application of EPC in(glioma.)
