Human Leukocyte Antigen DR Expression on Monocytes in Patients with Hospital Acquired Pneumonia: Prediction of Prognosis
- VernacularTitle:医院获得性肺炎患者单核细胞人类白细胞抗原DR表达与预后
- Author:
Shu LEI
;
Jihong CHEN
;
Yanchun WU
;
Lingcong WANG
;
Jiannong WU
;
Yihui ZHI
;
Xuehui YE
- Publication Type:Journal Article
- Keywords:
Hospital acquired pneumonia;
Human leukocyte antigen DR expression on monocytes;
APACHE Ⅱ score
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the clinical value of human leukocyte antigen DR(HLA-DR) expression on monocytes in prediction of prognosis in patients with hospital acquired pneumonia(HAP).METHODS A total of 68 patients suffered from HAP and transferred to intensive care unit(ICU) were enrolled in the study and divided into survivors group and nonsurvivors group according to prognosis.HLA-DR expression on monocytes,acute physiology,age and chronic health evaluation((APACHE)) Ⅱ score,serum cortisol level,T lymphocytes(subpopulation) and natural killer(NK) cell were observed.Relationship between HLA-DR expression on(monocytes) and APACHE Ⅱ score and 28-day mortality rates was analyzed through Logistic regression model.(RESULTS) HLA-DR expression on monocytes in nonsurvivors was significantly lower than that in survivors (P
