Distribution and Drug Resistance of Clinical Pseudomonas aeruginosa Isolates
- VernacularTitle:铜绿假单胞菌临床分离株医院感染分布及耐药性
- Author:
Jiayang QIU
;
Qiuming QU
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
Antibiotic;
Drug resistance
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the distribution and drug resistance of clinical Pseudomonas aeruginosa (isolates),and offer reasonable experimental data for clinical therapy.METHODS A statistic analysis for the(specimen) source,departments with infection and drug resistance condition to 218 isolates was conducted in(retrospective) manner.RESULTS Among 218 strains 138(63.3%) come from sputum and throat mucus,and 25(11.5%) from wound swab;the proportion of these strains from ICU was 44.9%,from neurology department was 12.4% and from(respiratory) department was 11.5%.The result of drug susceptibility showed that P.aeruginosa had a high resistance rate to the ?-lactamases, aminoglycosides,fluoroquinolones and sulfanilamides(antibiotics),respectively,accounted for more than 50%,and had a lower resistance rate to carbapenem, ?-(lactamases) antibiotics/inhibitor,the lowest was to piperacillin/tazobactam(8.7%),and to cefoperazone/(sulbactam)(17.5%).CONCLUSIONS Clinical(isolates) of P.aeruginosa come from the sputum,(pharyngeal) swab and ICU mainly,but their resistant rates are rather high and multidrug-resistant.We should pay more attention to the surveillance of antimicrobial resistance of P. aeruginosa in clinics and prevent(transmission) and epidemic of their resistance strains.
