Serum IL-12 Level in Mice Infected with Trichinella spiralis
- VernacularTitle:旋毛虫感染小鼠血清IL-12水平的动态观察
- Author:
Qihui WAN
;
Jiali WANG
;
Lifang HE
;
Hui LIU
;
Xi ZHANG
- Publication Type:Journal Article
- Keywords:
Trichinella spiralis;
Mice;
Interleukin-12
- From:
Chinese Journal of Parasitology and Parasitic Diseases
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Kunming mice were infected by feeding 150?5 larvae of Trichinella spiralis,established was also a normal control group.Blood was collected from the ophthalmic venous plexus respectively on 7 d,21 d,35 d and 49 d after infection and IL-12 in the serum was detected by ELISA.The level of IL-12 in serum decreased in groups of 7 d,21 d,and 35 d,with a significant difference to the control(P0.05),suggesting that the serum IL-12 of the Trichinella spiralis-infected mice significantly decreased at the earlier stage but approached to normal at a later stage.