Therapautic effects of treating intracranial hypertension with different dosage Mannitol alone or combined with Furosemide
- VernacularTitle:不同剂量甘露醇单用或合用速尿治疗颅高压的疗效观察
- Author:
Zhigang WANG
;
Yong JI
;
Xuan DING
- Publication Type:Journal Article
- Keywords:
Mannitol;
Furosemide;
intracranial hypertension;
plasma osmolarity;
renal function
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of treating intracranial hypertension(ICP) with different dosage Mannitol alone or combined with Furosemide.Methods 60 patients with high ICP after all kinds of operations on cranium and brain were divided into 4 groups according to the dosage of Mannitol alone or combined with Furosemide: 0.5 g/kg Mannitol(group A),1.0 g/kg Mannitol(group B),0.5 g/kg Mannitol and 20 mg Furosemide(group C),1.0 g/kg Mannitol and 20 mg Furosemide(group D).The effective power,rebound ratio,average effective time,average amplitude of decreasing ICP,plasma osmolarity and renal function were evaluated by monitoring intracranial pressure.Results In response of the effective power,rebound ratio of ICP and average effective time,groups C and D were more noticeable than groups A and B(all(P
