Relative Analysis of Pseudomonas aeruginosa Strain in Hospital Infection
- VernacularTitle:医院感染铜绿假单胞菌菌株亲缘性分析
- Author:
Jidong WANG
;
Hui JIN
;
Zuhuang MI
;
Min YU
- Publication Type:Journal Article
- Keywords:
Hospital infection;
Pseudomonas aeruginosa;
Multidrug resistance;
Clonal transmission
- From:
Chinese Journal of Nosocomiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the relationship of Pseudomonas aeruginosa strain in hospital infection. METHODS ?-Lactamase gene,aminoglycoside modification enzymes(AMEs)gene,and resistant antiseptic(qacE△1-sul1)gene were detected to mutidrug resistant P.aeruginosa with polymerase chain reaction(PCR) and we conducted cluster analysis of the molecule marked drug resistance gene. RESULTS PCR showed the positive ratios of TEM,CARB and VIM genes were 24.32%,43.24%,and 5.4%,respectively,While SHV,CTX-M,OXA-10 group,PER,GES,VEB,DHA,and IMP genes were all negative,the deleted ratio of oprD_2 gene was 86.49%;the positive ratios of aac(6′)-Ⅰ,aac(6′)-Ⅱ,ant(3″)-Ⅰand ant(2″)-Ⅰgenes were 8.11%,43.24%,18.91%,and 40.54%,respectively and the positive ratio of qacE△1 gene was 51.35%,There were clone transmitted phenomenon. CONCLUSIONS Hospital P.aeruginosa infection can induce clone transmitted hospital infection and it has fulminant prevalence.
