Acute Phase Protein in Gynecological Patients with Nosocomial Infection During Chemotherapy
- VernacularTitle:医院感染诊治中急性时相蛋白的变化研究
- Author:
Xianyong WEN
;
Yan ZHENG
;
Chengyu XIANG
;
Yanying LIN
- Publication Type:Journal Article
- Keywords:
Nosocomial infection;
Acute phase protein;
C-reactive protein;
Serum amyloid A;
?_1-Acid glycoprotein;
?_1-Antitrypsin
- From:
Chinese Journal of Nosocomiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the value of acute phase protein in the diagnosis and therapy for nosocomial infection monitoring. METHODS The levels of serum C-reactive protein(CRP),serum amyloid A(SAA),?_1-acid glycoprotein(AAG),and ?_1-antitrypsin(AAT) were measured in 71 gynecological patients with nosocomial infection during chemotherapy,Thirty normal controls and 33 chemotherapy patient controls were detected by nephelometry and compared with white blood cell counts. RESULTS The nosocomial infection rate of chemotherapy patients was 16.7%.Main pathogens were Gram-negative bacteria(60.6%).Fungi infection rate was 19.7%.The most frequent hospital infection sites were respiratory tract,gastrointestinal tract and wound.Compared with controls,the levels of serum CRP,SAA,AAG and AAT were significantly higher in chemotherapy patients with bacteria infection(P
