The Effect of Liquiritin on Body Weight and Behavior of Depressive Rats
- VernacularTitle:甘草苷对抑郁模型大鼠体重及行为学的影响
- Author:
Zhiyu ZHAO
;
Weixing WANG
;
Hongzhu GUO
- Publication Type:Journal Article
- Keywords:
depression model;
animal studies;
liquiritin;
body weight;
behavior
- From:
Chinese Mental Health Journal
2002;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of liquiritin on body weight and behavior in depression model rats.Methods:Seventy-two male Sprague-Dawley(SD)rats were randomly assigned into normal control group,model group(stress+vehicle),fluoxetine group(stress+ fluoxetine)and three liquiritin groups(stress+liquiritin at different dose).The behavior of rats was detected by sucrose consumption test and forced swimming test.Results:The model rats showed significantly lower body weight(429?45/494?37,P
