Effects of whole-body irradiation with X-rays on apoptosis in mouse splenocytes and peritoneal macrophages
- VernacularTitle:X射线全身照射对小鼠脾细胞和腹腔巨噬细胞凋亡的影响
- Author:
Ning WU
;
Yongzhe LIU
;
Ruiming XU
;
Yang LIU
;
Shunzi JIN
- Publication Type:Journal Article
- Keywords:
radiation,ionizing;
splenocytes;
macrophages;
apoptosis
- From:
Journal of Jilin University(Medicine Edition)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of whole-body irradiation(WBI)with different doses of X-rays on apoptosis in mouse splenocytes and peritoneal macrophages.Methods The apoptosis percentages of mouse splenocytes and peritoneal macrophages were detected with flow cytometry(FCM)at different time after the whole-body X-irradiation using the staining of Annexin-V and PI.Results As compared with the control,the percentage of apoptosis in mouse splenocytes began to increase gradually 24 h after WBI with 2 Gy X-rays(P
