Effect of hepatocyte growth factor on transvascular metastasis of sarcoma cells
- VernacularTitle:肝细胞生长因子在纤维肉瘤细胞血行转移中的作用
- Author:
Hua XIN
;
Yajuan ZHENG
;
Zhenguo HAN
- Publication Type:Journal Article
- Keywords:
hepatocyte growth factor;
fibrosarcoma;
neoplasm metastasis
- From:
Journal of Jilin University(Medicine Edition)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of hepatocyte growth factor(HGF) on transvascular metastasis of sarcoma cells.Methods The models of intravascular and extravascular migration of tumor cells in vitro were used to observe transvascular metastasis of sarcoma cells(HT1080).Results HT1080 migrated through basement membrane into blood vessels,and migrated through a gap between adjacent endothelial cells into extracellular matrix.The greater number of transmigrated HT1080 treated with HGF was observed(P
