Expressions of MMP-2 and TIMP-2 in lung cancer tissue and their relationships with microvessel density
- VernacularTitle:MMP-2和TIMP-2在肺癌组织中的表达及其与微血管密度的关系
- Author:
Hui SHENG
;
Chunli YUAN
;
Honglan ZHOU
;
Yishu WANG
- Publication Type:Journal Article
- Keywords:
carcinoma,non-small-cell lung;
metalloproteinase 2;
tissue inhibitor of metalloproteinase-2;
microvessel density
- From:
Journal of Jilin University(Medicine Edition)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions of metalloproteinase 2(MMP-2) and tissue inhibitors of metalloproteinase 2(TIMP-2) in lung cancer,and their relationships with microvessel density(MVD).(Methods The) expressions of MMP-2,TIMP-2 and Ⅷ factor were tested by immunohistochemical staining in(90 cases) of lung cancer tissue and 40 cases of para-cancer lung tissue.Results The immunohistochenmical staining results analyzed by IPP software indicated that MMP-2 and TIMP-2 expressed in all pathological types of lung cancer.The expreesion level of MMP-2 in lung cancer tissue was higher than that in para-cancer tissue(P
