Relationship between anti-trophoblast membrane antigens antibodies and hypertensive disorders complicating pregnancy
- VernacularTitle:抗滋养细胞膜抗原抗体水平与妊娠期高血压疾病的关系
- Author:
Yanli BAN
;
Hong TENG
;
Fengjie LIU
;
Hongwei QI
;
Yongchun CHANG
- Publication Type:Journal Article
- Keywords:
pregnancy complications,cardiovascular;
eclampsia;
trophoblasts/immunology;
antibodies
- From:
Journal of Jilin University(Medicine Edition)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between anti-trophoblast membrane antigens(TA) antibodies and hypertensive disorders complicating pregnancy(HDCP).Methods Enzyme linked immunosorbent assay(ELISA) was used to detect anti-TA IgG and IgM in both maternal and umbilical serum samples of 40 normal pregnant women and 92 HDCP women(23 gestational hypertension or mild preeclampsia,41 severe preeclampsia and 28 eclampsia).Results The positive rates of anti-TA IgG and IgM in maternal serum samples with HDCP,eclampsia or severe preeclampsia were significantly higher than that in normal pregnant women,the positive rate of anti-TA IgM increased significantly with the aggravation of HDCP(P
