Relationships between COX-2 and VEGF expressions and angiogenesis and clinical pathology in thyroid cancer
- VernacularTitle:甲状腺癌COX-2和VEGF的表达与血管生成及临床病理的关系
- Author:
Bai JI
;
Guangyi WANG
;
Ping ZHANG
;
Zijun YANG
;
Shuang LI
- Publication Type:Journal Article
- Keywords:
cyclooxygenase-2;
angiogenesis factor;
thyroid neoplasms;
immunohistochemistry
- From:
Journal of Jilin University(Medicine Edition)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationships between Cyclooxygenase(COX-2) and angiogenesis and expressions of COX-2 and vascular endothelial growth factor(VEGF) in thyroid cancer and its clinical significance.Methods Immunohistochemistry was used to detect the expressions of COX-2 and VEGF in 60 thyroid cancer,(15 thyroid)adenomas and 10 normal thyroid tissues.Results The expression rates of COX-2 and VEGF in thyroid cancer were higher than those in thyroid adenomas and normal tissues(P
