Alteration of serum Cystatin C concentrations in patients with hepatopathy infected with hepatitis B or C virus
- VernacularTitle:感染HBV或HCV的肝病患者血清半胱氨酸蛋白酶抑制剂C的改变
- Author:
Jiafu FENG
;
Tingmei CHEN
;
Zhiguang TU
- Publication Type:Journal Article
- Keywords:
Cystatins;
Tissue inhibitor of metalloproteinases;
Hepatitis,viral,human
- From:
Chinese Journal of Laboratory Medicine
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical application of Cystatin C as a biological marker for monitoring hepatic pathological change in patients with virus hepatitis.Methods Two hundred and seven patients infected with hepatitis B or C virus(HBV, HCV)were divided into cirrhosis group(group A),chronic HBV group(group B),chronic HCV group(group C),and liver cancer group(group D). 32 healthy controls(group H) were recruited . The serum TIMP-1,TIMP-2,and Cystatin C as well as some traditional markers for monitoring liver function and renal function including creatinine, creatinine clearance rate, alanine transaminase, and aspartate transaminase were determined.Results In these groups, serum Cystatin C(F=28.334, P
