Research advances on dermal stratum corneum and its injury
- VernacularTitle:皮肤角质层及其损伤的研究进展
- Author:
Minhong PAN
;
Xiaojun ZHOU
;
Shaojun JIANG
- Publication Type:Journal Article
- Keywords:
Stratum corneum;
Injury;
Repair
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Stratum corneum,the outermost layer of the mammalian skin, has its unique structural,biophysical and biochemical characteristics.The form of stratum corneum is a continuous sheath of protein-enriched corneocytes embedded in an intercellular matrix enriched in nonpolar specialized lipids.It provides an impermeable barrier from exogenous noxious substances and prevents the body from transdermal water loss.Recent researches suggest that its morphological and functional abnormalities can be induced by various environmental effects such as ultraviolet radiation,mechanical friction,organic solvents,etc.However,the mechanism of the injury-repair process remains unclear.Several cytokines and ceramide may be involved in the regulation.
