Design of a Detection System of Leaky Surface Acoustic Wave Biosensor in Liquid Phase and Test of HPV
- VernacularTitle:漏声表面波生物传感器液相检测系统的构建及检测HPV的实验研究
- Author:
Yunxia WANG
;
Weiling FU
;
Ming CHEN
;
Yi DING
;
Liang CAO
- Publication Type:Journal Article
- Keywords:
Leaky surface acoustic wave;
Biosensor;
Delay line;
Phase
- From:
Chinese Journal of Nosocomiology
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To design the detection system of the leaky surface acoustic wave(LSAW) biosensor in(liquid) phase and detect human papilloma virus(HPV) target sequence with the LSAW biosensor.METHODS A detection delay line and a reference delay line were constructed,the phase of the two delay line changes was(evaluated) in liquid phase,and real time monitoring of HPV reaction was performed by using the LSAW biosensor system.RESULTS The phase of the two delay lines had different changes in liquid phase;HPV could lead to a great change of the phase in the detection delay line,and reference delay line had no change.CONCLUSIONS The(detection) system of the LSAW biosensor in liquid phase is successfully constructed and real time monitoring of(detection) of HPV is realized.
