Research on piezoelectric immunosensor for detection of antibody to hepatitis C virus
- VernacularTitle:压电免疫传感器用于抗丙型肝炎病毒抗体检测的实验研究
- Author:
Yanxia LI
;
Zhongming LIU
;
Shuihua ZHANG
;
Caixia LI
- Publication Type:Journal Article
- Keywords:
anti-hepatitis C virus;
piezoelectric immunosensor;
detection
- From:
Chinese Journal of Clinical Laboratory Science
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develope a new kind of piezoelectric immunosensor which could detect anti-HCV antibody in short time.Methods The corresponding sensitive material was fixed on the piezoelectric immunosensor by polyethylenimine adhesion and glutaraldehyde cross-linking method.The assembly condition and response characters were investigated and the piezoimmunosensor could be used in detection of clinical blood specimen.Results The respond of the positive serum was 4 times higher than that of negative serum.HBsAg had little interference to the detection of anti-HCV antibody.Conclusion The piezoelectric immunosensor prepared in this study is highly selective,easy to be operated for effective detection of anti-HCV antibody.
