The changes of HNP and NE content in serum during perioperation of cardiac surgery under cardiopulmonary bypass
- VernacularTitle:体外循环围手术期患者血浆中性粒细胞肽和弹性蛋白酶的动态观察
- Author:
Yongjie WANG
;
Yucai ZHANG
;
Xinjian GONG
;
Dong WANG
;
Xi LI
;
Jianguo WU
- Publication Type:Journal Article
- Keywords:
Cardiopulmonary Bypass;
HNP;
NE
- From:
Chinese Journal of Clinical Laboratory Science
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of HNP1-3 and NE content in serum quantitatively during perioperation of cardiac surgery under cardiopulmonary bypass(CPB),and to explore the role of changes of HNP1-3 and NE content in early diagnosis of system inflammatory response syndromes(SIRS)after cardiopulmonary bypass.Methods The contents of HNP1-3 and NE in serum during perioperation of 21 cardiac surgeries under cardiopulmonary bypass were measured quantitatively using ELISA method,and the contents of CK,CK-MB and C-RP in serum were measured at the same time points as that of HNP1-3 and NE.Results The contents of HNP1-3 and NE in serum were 54.55?26.45 ng/ml and 41.09?9.93 ng/ml respectively before CPB,and they were 435.45?500.13 ng/ml and 250.91?97.21 ng/ml respectively 0.5 h after CPB which were significantly higher than that before CPB(P
