An experimental study of the nanometer ceramics artificial bone in repairing bone defects
- VernacularTitle:纳米陶瓷人工骨修复骨缺损的实验研究
- Author:
Jiande XIAO
;
Jianyi XIONG
;
Kan OUYANG
;
Al EL
- Publication Type:Journal Article
- Keywords:
Nano-material;
Ceramics;
Artificial bone;
Bone defect
- From:
Chinese Journal of Orthopaedic Trauma
2004;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the feasibility of applying nanometer ceramics artificial bone in clinical repair of bone defects. Methods The animal models of bone defect was made on the unilateral radius of 45 New Zealand white rabbits, which were divided into experimental group(repair with nanometer ceramics artificial bone), control group (repair with ceramics artificial bone) and blank group (unrepaired) randomly. The reconstructive effect in each group was evaluated by gross observation, alkaline phosphatase(ALP) detection of blood serum, histopathological observation, X-ray examination and SEM detection at 4th, 8th and 12th weeks postoperatively. Results In the experimental group there was more bone formation than in the control and the blank groups. The differences in reconstructive effect were statistically significant ( P
