Molecular and Chemical Mechanism of Trichomonas vaginalis-induced Contact-dependent Cytotoxicity
- VernacularTitle:阴道毛滴虫接触依赖性细胞毒性的分子作用及化学基础
- Author:
Shuguo YANG
;
Chaonan TIE
;
Yajing WANG
- Publication Type:Journal Article
- Keywords:
Trichomonas vaginalis;
Contact-dependent cytotoxicity;
Pathogenesis
- From:
Chinese Journal of Parasitology and Parasitic Diseases
1997;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Trichomonas vaginalis parasitizes in human genitourinary tract.The protozoon adhering to target cell plays a critical role in its contact-dependent cytotoxicity.The enzymes synthesized by T.vaginalis can hurt vaginalis epithelial cells(VECs)directly.The focal immune reaction in the location parasitized by the parasite may provide an immunologic protection.Meanwhile,inflammatory factors and immune cells may aggravate the situation.In general,the T.vaginalis-induced contact-dependent cytotoxicity is a result of the involvement of some molecular and chemical factors.
