Controlled release of interferon tau from chitosan-alginate microcapsules
- VernacularTitle:壳聚糖-海藻酸钠微囊对干扰素-tau的控释作用
- Author:
Jialei FU
;
Changzheng SONG
;
Genglin ZHANG
- Publication Type:Journal Article
- Keywords:
interferon tau;
chitosan;
sodium alginate;
encapsulation rate;
microcapsule
- From:
Chinese Journal of Marine Drugs
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The microcapsules were prepared by using chitosan and sodium alginate as wall materials,and the controlled-release microcapsulas of interferon tau were hoped to be develop an oral interferon preparation.Methods The microcapsules were prepared by using syringe hand-made drop.In the process of dropping,speed and distance were the major factors which influence the form of microcapsules.Results Chitosanalginate microcapsules which was prepared simple and fast had high encapsulation rate and extended-release effect in intestine.Conclusion Chitosan-alginate microcapsules have the potential to be used to prepare interferon tau and other protein medicines.
