Changes in plasma pro-brain natriuretic peptide concentration before and after interventional therapy in congenital heart diseases
- VernacularTitle:先天性心脏病介入治疗前后脑利钠肽前体水平的比较
- Author:
Jianglin LI
;
Yufen LI
;
Zhiwei ZHANG
- Publication Type:Journal Article
- Keywords:
Natriuretic peptide, brain;
Heart defects, congenital
- From:
Chinese Journal of Interventional Cardiology
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between plasma pro-brain natriuretic peptide (N-pro-BNP) level and heart function, as its well as change before and after interventional therapy. Methods Fifty-eight children with left to right shunt congenital heart diseases were enrolled from July, 2004 to Jan, 2005. Clinical heart function were categorized and plasma N-pro-BNP concentration were detected. The ejection fraction (EF), fractional shortening (FS) and left ventricular and diastolic dimension (LVDd) were measured by two-dimensional echocardiography. The relationship between plasma pro-BNP concentration and the echo parameters, and its change before and after interventional therapy were analyzed. Results The plasma N-pro-BNP concentration, LVDd, EF and FS before and after intervention were 194.7?154.7 ng/L vs 561.0?594.2 ng/L (P
