Study on antibiotic resistance of Neisseria gonorrhoeae in Nanning for 5 years
- VernacularTitle:南宁地区五年淋病奈瑟菌耐药监测研究
- Author:
Bangyong ZHU
;
Xiumei ZHAO
;
Shanlie QIN
;
Shiyuan LI
;
Quan GAN
;
Yuejin LIANG
- Publication Type:Journal Article
- Keywords:
Neisseria gonorrhoeae;
Drug monitoring;
Anti-bacterial agents
- From:
Chinese Journal of Laboratory Medicine
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the antibiotic resistance of Neisseria gonorrhoeae and the prevalence of penicillinase-producing Neisseria gonorrhoeae (PPNG) and high-level tetracycline resistant Neisseria gonorrhoeae (TRNG) in Nanning. Methods Minimum inhibitory concentrations (MIC) were determined by agar dilution method and ?-lactamase production was comfirmed by acidometric method.Results Among 458 strains, 33 strains(7.20%) were found to be PPNG and 231 strains(50.44%) were TRNG. The resistance rate to ciprofloxacin, ceftriaxone and spectinomycin were 87.33%, 1.31% and 0.22% respectively. Conclusion The situation of resistance to ciprofloxacin was very serious, and it was also found that a few of gonococcal isolates were resistant to ceftriaxone and spectinomycin. The study showed that it is important to successively survey the antibiotic resistance of Neisseria gonorrhoeae.
