Influence of Batroxobin on plasma level of lysophosphatidic acid in patients with acute cerebral infarction
- VernacularTitle:巴曲酶对急性脑梗死患者血浆溶血磷脂酸水平的影响
- Author:
Wenhui ZHU
;
Juan YU
;
Xiushi NI
- Publication Type:Journal Article
- Keywords:
Batroxobin;
acute cerebral infarction;
lysophosphatidic acid
- From:
Journal of Clinical Neurology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of Batroxobin on plasma level of lysophosphatidic acid(LPA) in patients with acute cerebral infarction.Methods A total of 61 patients with acute cerebral infarction were selecued randomly to Batroxobin group ( n=31) or control group ( n=30). Aspirin and Danshen root were used in both groups as basic treatment. Batroxobin was used in Batroxobin group for one course of treatment. The plasma levels of LPA were measured before treatment and 5th, 7th, 10th, and 14th day after treatment in both acute cerebral infraction groups, and compared with health volunteers(normal group).Results The plasma levels of LPA in both Batroxobin group and control group were remarkably higher than that in normal group(all P0.05). In Batroxobin group the plasma levels of LPA were significantly lower than that in control group at 5th, 7th, 10th, 14th day after treatment(all P