Relationship between the expression of c-erbB-2,nm-23,ER,PR and five-year tumour-free survival time in primary breast cancer
- VernacularTitle:c-erbB-2及nm-23和女性激素受体的表达与乳腺癌患者5年无瘤生存的关系
- Author:
Min DONG
- Publication Type:Journal Article
- Keywords:
Breast carcinoma;
c-erbB-2;
nm-23;
Estrogen receptor;
Immunohistochemistry;
Survival time;
Prognosis
- From:
Journal of Medical Postgraduates
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the relationship between the expression of c-erbB-2,nm-23,ER,PR and five-year tumour-free survival time in primary breast cancer.Methods:Seventy-four breast cancer patients with expressions of c-erbB-2,nm-23,ER,PR were detected by using immunohistochemical S-P methods.Results:In the multiplicity,the expression of c-erbB-2 had negative correlation with five-year tumor-free survival time,while the expression of ER had positive correlation with five-year tumor-free survival time.In the mono factor analysis,the expression of nm-23 had positive correlation with five-year tumor-free survival time.Conclusion:Both c-erbB-2,nm-23 and ER could be considered as a prognostic value for breast cancer.The positive of c-erbB-2 may be related to poorly prognosis.The positive of ER and nm-23 may be related to a higher survival time.
