Gene therapy in reparation of cartilage lesions
- VernacularTitle:治疗基因局部转染修复关节软骨损伤的研究进展
- Author:
Ting GUO
;
Jianning ZHAO
- Publication Type:Journal Article
- Keywords:
Articular cartilage;
Gene;
Growth factors
- From:
Journal of Medical Postgraduates
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Damaged articular cartilage has a limited intrinsic capacity to heal itself,especially in adults,It represents a clinical challenge.Novel gene therapy can introduce particular beneficial gene into the seeded sells and express growth factors or other therapy proteins at the repair site.Gene therapy focuses on selecting proper gene,target cells and the transferring systems. The tissue engineering cartilage with gene-modified seeding cells and transferring objective gene to target sells locally present new therapeutic regimens for repairing defects in articular cartilage.
