Effects on local immunological functions after radiofrequency ablation for primary hepatocellular carcinoma
- VernacularTitle:原发性肝癌射频治疗后局部免疫功能的变化及其临床意义
- Author:
Yanbin WANG
;
Minhua CHEN
;
Kun YAN
- Publication Type:Journal Article
- Keywords:
Primary hepatocellular carcinoma;
Radiofrequency ablation;
Immunohistochemistry;
Heat shock protein 70;
Tumor infiltrating lymphocytes
- From:Chinese Journal of Minimally Invasive Surgery
2005;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
4 cm in diameter(Z=1.966,P=0.048).A positive relation was seen between HSP70 expression and CD8~+ T cell number at the border zone of RFA sphere(r=0.489,P=0.046).The HSP70 expression and the CD8~+ T cell number at the border zone of RFA sphere were higher in recurrence-free patients than in recurrent patients,respectively(Z=2.009,P=0.045;Z=2.007,P=0.045).Conclusions Following the RFA,the HSP70 expression and the CD8~+ T cell number at the border zone of RFA sphere will be elevated,indicating that RFA induces an immune response against tumor antigens and a tumor-specific T cell reaction.
