Insulin resistance and function of islet ? cell of the first-degree relatives of T2DM with normal glucose tolerance
- VernacularTitle:2型糖尿病患者一级亲属正常糖耐量人群胰岛素抵抗与胰岛?细胞功能的研究
- Author:
Na WANG
;
Yanhu DONG
;
Weiwei QIAN
- Publication Type:Journal Article
- Keywords:
First-degree relative;
Diabetes mellitus,type 2;
Insulin resistance;
Insulin secretion
- From:
Chinese Journal of Diabetes
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the insulin resistance and insulin secretion of the first degree relatives of T2DM with normal glucose tolerance(NGT). The levels of FIns and HOMA-IR in the groups of the parental (n=35) and the maternal (n=58) were higher than that in the group of the paternal (n=42), bwt the IAI and △I_ 30 /△G_ 30 were lower than that in the group of paternal. This suggests the first-degree relatives of type 2 diabetes have insulin resistance and impaired first phase insulin secretion in NGT.
