Value of HBsAb Positive and Detection of HBV-DNA in Selection of Blood Source and Organ Transplantation
- VernacularTitle:抗-HBs阳性与HBV-DNA检测在选择血源及器官移植中的意义
- Author:
Bing ZHU
;
Zhengyang YU
;
Yan PENG
;
Hong YOU
- Publication Type:Journal Article
- Keywords:
HBsAb;
HBV-DNA;
Viral replication;
infectivity
- From:
Chinese Journal of Nosocomiology
2004;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the HBV-DNA level and its replication with only HBsAb positive for transplantation. METHODS Serial serum samples were studied with the quantitative determination of HBV-DNA by a quantitative PCR assay and determination of HBsAb by ELISA. RESULTS The positive rate of HBV-DNA was 8.4% in the patients with only HBsAb positive and that was 11.11% in the patients who had not been injected with vaccine;the level of HBV-DNA in 11 samples was less than 10~4 copies/ml and five samples showed the amount between 10~4-10~6 copies/ml.The positive rate of HBV-DNA was 8.4% in the patients with only HBsAb positive and that was 11.11% in the patients who had not been injected with vaccine;the level of HBV-DNA in 11 samples was less than 10~4 copies/ml and five samples showed the level between 10~4-10~6 copies/ml. CONCLUSIONS Patients with only HBsAb positive are still infective,which should be paid attention in transplantation.
