An Anti-apoptotic Protein Expressed Specifically and Highly in The Cardiac Tissue:ARC
- VernacularTitle:心脏特异性高度表达的抗凋亡蛋白——ARC
- Author:
Yuzhen LI
- Publication Type:Journal Article
- Keywords:
apoptosis repressor with caspase recruitment domain(ARC), myocardial apoptosis, anti-apoptotic protein
- From:
Progress in Biochemistry and Biophysics
2006;0(09):-
- CountryChina
- Language:Chinese
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Abstract:
Many apoptosis-related heart diseases such as myocardial infarction, cardiomyopathies, and heart failure severely impair human's health and life. Currently, a key focus for the medical researchers is to find out effective ways to prevent or treat these heart diseases. ARC (apoptosis repressor with caspase recruitment domain) is the first anti-apoptotic protein so far identified to be highly and specifically expressed in the cardiac tissue. ARC could be structurally phosphorylated and involved in various signaling pathways during apoptosis.
