Relationships among autonomic nervous function,reflux symptoms and esophageal motility in patients with gastro-esophageal reflux disease
- VernacularTitle:GERD患者自主神经功能与反流症状及食管动力的关系
- Author:
Xiaohong SUN
;
Meiyun KE
;
Zhifeng WANG
- Publication Type:Journal Article
- Keywords:
gastro-esophageal reflux disease;
autonomic nerve function;
esophageal motility;
reflux symptom
- From:
Basic & Clinical Medicine
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of autonomic nervous dysfunction on pathogenesis of gastro-esophageal reflux disease(GERD).Methods Autonomic nervous function(ANF) was assessed by cardiovascular reflex tests in healthy volunteers and patients with GERD;Based on the ANF test results,the relationship between the impairment degree of autonomic nerve and the esophageal motility or the reflux esophagitis or the score of reflux symptoms was investigated.Results ① 59.5% of patients with GERD have abnormal ANF and the rate in GERD patients is much higher than that in healthy volunteers,parasympathetic nerve impairment is predominant.② The score of reflux symptoms in patients with normal ANF is significantly lower than that in patients with abnormal ANF(6(2,7.6)vs 9(4.1,17),P
