Plasma CGRP,Ang Ⅱ And ET in Healthy Offspring with Family History of Essential Hypertension
- VernacularTitle:有高血压家族史的健康子代血浆中降钙素相关肽,血管紧张素及内皮素水平
- Author:
Lan LIU
;
Bo ZHANG
;
Junling GAO
;
Yuhong ZHANG
- Publication Type:Journal Article
- Keywords:
Calcitonin gene related peptide;
Angiotensin Ⅱ;
Endothelin;
Hypertension
- From:
Chinese Journal of Hypertension
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study CGRP,Ang Ⅱ and ET in healthy offsprings from different families history of essential hypertension. Methods Sixty healthy offsprings with or without a family history of essential hypertension were recruited and divided into two groups: (1) 30 from family with either one parent of essential hypertension; (2) 30 from family with both parents of essential hypertension; (3) control group,30 subjects from family with parents negative history.The levels of plasma CGRP,Ang Ⅱ and ET were determined by radioimmunoassay. Results The plasma levels of CGRP,Ang Ⅱ in one parent group were(28.3?10.4 pg/mL),(52.5?11.1 pg/mL) and (37.7?14.7 pg/mL),(58.4?9.1 pg/mL) in both parents group,which were increased significantly as compared with those in the control group (CGRP 19.9?10.5 pg/mL,Ang Ⅱ 45.3?9.9 pg/mL,P
