Extended Spectrum ?-Lactamases Genes in Multidrug-resistant Pseudomonas aeruginosa
- VernacularTitle:多重耐药铜绿假单胞菌产超广谱?-内酰胺酶基因研究
- Author:
Dong CHANG
;
Wei JIANG
;
Hua WEI
;
Chunxin WANG
;
Yunjie ZHANG
;
Zuhuang MI
- Publication Type:Journal Article
- Keywords:
?-Lactamases;
Resistant genes;
Pseudomonas aeruginosa
- From:
Chinese Journal of Nosocomiology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the situation of prevalence for extended spectrum ?-lactamases(ESBLs)genes in multidrug-resistant Pseudomonas aeruginosa(PA). METHODS Antimicrobial susceptibility test was performed by agar dilution method and 7 kinds of ESBLs genes were detected by PCR methods in 35 strains of PA. RESULTS In 35 strains of PA, the positive rates of genes of TEM, OXA, PER and GES were 51.4%, 42.8%, 31.4%, and 22.9%, respectively, and genes of SHV, VEB, and CTX-M-1 were all negative. CONCLUSIONS This study shows that there are high positive rates of TEM, OXA, PER and GES genes in PA in our hospital. The GES genes in PA are first reported in China.
