Expression of Fibronectin in Hepatic Tissues from Patients with Hepatitis
- VernacularTitle:肝炎患者肝组织内纤连蛋白表达变化的研究
- Author:
Haibin WANG
;
Xinhui SHI
;
Yunjie ZHANG
;
Dongqing ZHANG
;
Na SUN
- Publication Type:Journal Article
- Keywords:
Fibronectin;
Hyaluronic acid;
Immunohistochemistry;
Hepatitis;
Hepatic cirrhosis
- From:
Chinese Journal of Nosocomiology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To examine expression and distribution of fibronectin (FN) in hepatic tissues from patients with hepatitis or cirrhosis, and its correlation with serum hyaluronic acid (HA) contents. METHODS The expression and distribution of FN were detected with immunohistochemical and pathological methods in liver tissues of 66 cases, among which there were 8 cases of normal liver tissues, 58 cases of various types of hepatitis. The levels of HA in patients with liver disease were detected with radioimmunological method. RESULTS Positive cellular rate of FN in hepatocytes and endothelial cells of chronic active hepatitis (CAH) was apparently higher than those in acute hepatitis (AH) group and chrouic persistent hepatitis (CPH) group(P
