Serum IL-18 Level in HBV-infected Patients and Its Clinical Significance
- VernacularTitle:乙型肝炎患者外周血细胞因子IL-18的检测及其意义
- Author:
Hua JIANG
;
Dan SHEN
;
Hong CAO
;
Hairong ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
Interleukin-18;
FQ-PCR
- From:
Chinese Journal of Nosocomiology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the relationship between HBV DNA and serum IL-18 level in patients with hepatitis B virus. METHODS They were divided by MEIA method into 3 groups. group A:HBsAg+, HBeAg+ and HBcAb +(A); group B:HBsAg+, HBeAb+ and HBcAb+(B); and group C:HBsAb+(as normal controls ). Serum IL-18 level was determined by ELISA method in hepatitis patients and normal controls and HBV DNA was determined continuously . RESULTS Concentration of serum IL-18 in patients with different type of viral hepatitis was significantly higher than those in healthy volunteers(P
