Pulmonary Infection Status, Drug-resistance and Risk Factors of Extended-spectrum ?-Lactamases-producing Bacteria
- VernacularTitle:肺部感染产超广谱?-内酰胺酶细菌的耐药性及危险因素分析
- Author:
Lin TENG
;
Fen SU
;
Ting LIU
;
Yongqiang ZHEN
;
Liping WU
;
Kaiyu SUN
;
Leqiang WANG
- Publication Type:Journal Article
- Keywords:
Extended-spectrum ?-lactamases;
Pulmonary infection;
Risk factors;
Drug-resistance
- From:
Chinese Journal of Nosocomiology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To survey the patient with pulmonary infection induced by extended-spectrum ?-lactamases-producing bacteria and their Enterobacteriaceae clinical characteristics, drug-resistance and countermeasure. METHODS Isolation, cultivation, identification, drug-sensitivity tests and confirmation of ESBLs-producing bacteria were done for the bacteria of sputum specimens collected from our hospital from Feb 2001 to Sept 2004. Susceptibility testing was performed by disk diffusion(K-B)method. RESULTS Totally 541 strains of Enterobacteriaceae were cultivated altogether and ESBLs-producing bacteria were 135 strains. The ESBLs- producing strains were sensitive to imipenem, and the resistance rates to it were 0.00% . The resistance rates of ESBLs-producing strains to cefoperazone/sulbactam and piperacillin/tazobactam were 31.11% and 44.44%, respectively . The multi-drug-resistance (MDR) rate of ESBLs-producing strains was higher than that of strains no producing ESBLs (P
