Association of class 1 integrons of Acinetobacter baumannii with resistance
- VernacularTitle:鲍曼不动杆菌Ⅰ类整合子系统与其耐药性关系的研究
- Author:
Daqing YANG
;
Yin TANG
;
Taicun LI
;
Liping SHI
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
gene-cassette;
class 1 integron;
resistance
- From:
Chinese Journal of Clinical Laboratory Science
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To monitor the distribution of class 1 integrons of Acinetobacter baumannii and interpret the association of class 1 integrons with the resistance in clinical isolates.Methods Susceptibility to 14 different antimicrobial agents was determined by agar dilution method.DNA of all clinical isolates was extracted to detect class 1 integrons by PCR.Results The differences between integron-positive isolates and integron-negative isolates was significant in the resistance to all tested antibiotics except for Imipenem,Cefepime and Cefoperazone plus Sulbactam.Different types of class 1 integrons showed different resistance types.Conclusions There were some close relations of class 1 integrons with multi-drug resistance as well as resistance types in Acinetobacter baumannii.