Transdermal enhancement of low-frequency ultrasound
- VernacularTitle:低频超声增透效应
- Author:
Haixia YU
- Publication Type:Journal Article
- Keywords:
low-frequency ultrasound;
cavitation;
sonophoresis;
stratum corneum
- From:
Chinese Medical Equipment Journal
2004;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
The transdermal enhancement of ultrasound was discovered 50 years ago.The advantages of low-frequency ultrasound in enhancing the transdermal transport of molecule were discovered in 40 years' study.Because the cavitation is easier to happen in lower frequency ultrasound,the transdermal enhancement of low-frequency ultrasound is higher.The inertial cavitations near the surface of skin play important roles in the transdermal enhancement of low-frequency ultrasound.There are many studies about the effects of the parameters of ultrasound on the transdermal enhancement of low-frequency ultrasound,but there are fewer studies about the effects of other factors.The transdermal enhancement of low-frequency ultrasound has been used for transdermal drug delivery.There are many studies about the transdermal monitoring of glucose and other analytes using low-frequency ultrasound.Many opportunities and challenges lie ahead.
