Study on the relationship of platelets activation and inflammatory reaction in hematoma at acute phase of intracerebral hemorrhage
- VernacularTitle:脑出血患者急性期血小板活化与血肿内炎性反应关系的研究
- Author:
Guohua ZHANG
;
Jie LIN
;
Caixiao CHEN
- Publication Type:Journal Article
- Keywords:
cerebral hemorrhage;
hematoma fluid;
leukocyte infiltration;
activated platelets;
inflammatory reaction
- From:
Journal of Clinical Neurology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the leukocyte infiltration inside the hematoma and the correlation between this and the expression of platelet P-selectin (CD62p) and platelet thrombin-sensitive protein (TSP) of patients with cerebral hemorrhage. Methods In 33 patients with cerebral hemorrhage treated with minimally invasive surgery, the expressions of platelet CD62p and TSP were detected by flow cytometry (FCM) and leukocyte counts were measured in intracerebral hematoma fluid and venous blood. The correlation analysis was performed between the two variables.Results The expressions of platelet CD62p and TSP in hematoma fluid were higher in patients with acute cerebral hemorrhage (20.25?1.82, 37.04?3.63) than those in venous blood (7.72?2.19, 12.32?2.81)(all P
