Study on dynamic changes of the serum concentration of soluble cell adhesion molecule in patients with aneurysmal subarachnoid hemorrhage
- VernacularTitle:动脉瘤性蛛网膜下腔出血患者血清可溶性黏附分子-1含量动态变化的研究
- Author:
Yong JI
;
Zhigang WANG
;
Zhong WANG
- Publication Type:Journal Article
- Keywords:
subarachnoid hemorrhage;
cerebral vasospasm;
soluble adhesion molecule-1
- From:
Journal of Clinical Neurology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the dynamic changes of serum concentration of soluble cell adhesion molecule (sCAM) in patients with aneurysmal subarachnoid hemorrhage.Methods Serum concentrations of sCAM in 30 patients with aneurysmal subarachnoid hemorrhage were detected using ELISA method before surgery and at 1~3 d, 7~9 d and 11~13 d after surgery. Transcranial Doppler sonography was used to measure the velocity of middle cerebral artery (VMCA). The results were compared with 20 healthy controls.Results Serum concentrations of sCAM at 1~3 d and 7~9 d in patient group were significantly higher than that in control group (all P