Valsartan Improves Endothelial Function in Essential Hypertension Patients
- VernacularTitle:缬沙坦改善原发性高血压患者血管内皮功能
- Author:
Li XU
;
Ruijin XU
- Publication Type:Journal Article
- Keywords:
] Valsartan;
Essential hypertension;
Endothelium-dependent dilation function;
Nitric oxide;
Malondialdehyde
- From:
Chinese Journal of Hypertension
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of valsartan on endothelial function in patients with essential hypertension. Methods Thirty six patients of essential hypertension recieved valsartan(80 mg/d) for 8 weeks. After treatment, serum NO, SOD and MDA were measured using chemically colorimetric method. Brachial artery endothelium-dependent dilation function(FMD) was determined by high resolution ultrasonography. Twenty six health adults served as controls. Results Compared with the control, FMD was significantly decreased (P
