Serum Free Fatty Acids Composition, Waist/Hip Ratio and insulin activity in Patients with Essential Hypertension
- VernacularTitle:高血压患者空腹血游离脂肪酸组成与腰臀比、胰岛素活性的关系
- Author:
Shun WANG
;
Aiqun MA
;
Shaowu SONG
;
Qinghai QUAN
;
Xiaohui ZHENG
;
Xinfeng ZHAO
- Publication Type:Journal Article
- Keywords:
Free fatty acid;
Essential hypertension;
?6 desaturase;
?-linolenic Acid
- From:
Chinese Journal of Hypertension
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of fasting serum FFA composition with central obesity, hypertension, insulin resistance, levels of serum zinc and age, gender-related differences. Methods Serum FFA were determined by high performance liquid chromatogram in 232 commuity|based subjects aged between 35 and 55 years: 109 hypertensives, 123 normotensives. Results Multivariate stepwise linear regression models and correlation analysis showed that serum FFA composition (including levels of n3PUFA, P/S ratio, C20:5/C18:3, C22:6/C20:5 and C20:4/C18:2 ratio) were linearly correlated with waist/ hip ratio, insulin sensitivity index, levels of serum zinc and related to the habit of diet (all P