Three-dimensional simulation of the structures of human N-acetyltransferase 2 protein molecule
- VernacularTitle:人类N-乙酰化酶2蛋白质分子的计算机三维模拟
- Author:
Zhiyuan ZHU
;
Jinheng LI
;
Weiwei LENG
;
Ying CHEN
- Publication Type:Journal Article
- Keywords:
N-acetyltransferase 2;
Protein structure;
Computer modeling
- From:
Journal of Medical Postgraduates
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To simulate human N-acetyltransferase 2 protein 3D model by computer technology. Methods: 3D model of human N-acetyltransferase 2 protein was simulated with protein list and computer technology,the physical,chemical,biological characteristics and the functions were analyzed.Results: The possible structure of NAT2 was simulated using ANTHEPORT5.0,a software for determining the sequence of protein,forecasting the pHi and molecular weight of NAT2 were 5.495 and(33 544) respectively.The titration curve and physics-chemistry characteristic curve of NAT2 were also obtained.A Helical Wheel chart was plotted,aiming at the fragment of NAT2 around amino acid 282 nd.Conclusion:The possible structure of NAT2 was simulated using computer,analysis and forecast was also carried out,the method was feasible to genetic analysis of NAT2.
