Role of macrophage migration inhibitory factor in mechanism and treatment of septic shock
- VernacularTitle:巨噬细胞移动抑制因子在脓毒性休克及其治疗中的作用
- Author:
Jianxiu GUO
;
Chuanmin HU
- Publication Type:Journal Article
- Keywords:
Macrophage migration inhibitory factor;
Cytokine;
Septic shock
- From:
Journal of Medical Postgraduates
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Macrophage migration inhibitory factor(MIF),a potential pro inflammatory cytokine,is a pivotal regulatory element in the nature and adapted immune.This article aims to introduce the histocellular sources,genetic structure,protein structure and biological activity of this cytokine,and further to explore its role in the pathogenesis of septic shock,and its antagonist in the treatment of this disease.