Genotyping of ?-Lactamases and Aminoglycoside Modifying Enzymes Genes from Acinetobacter baumannii
- VernacularTitle:鲍氏不动杆菌?-内酰胺酶和氨基糖苷类修饰酶基因研究
- Author:
Zhongnong ZHAO
;
Xiaomao QIAN
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
?-Lactamases;
Aminoglycoside modifying enzymes;
Genes
- From:
Chinese Journal of Nosocomiology
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the genotyping of ?-lactamases and aminoglycoside modifying enzymes on Acinetobacter baumannii isolated in Shaoxing. METHODS Thirty nine strains of A.baumannii were isolated from hospitalized patients,and drug-resistant genes were detected by PCR. RESULTS The detection rates of ?-lactamases coding genes of TEM and OXA-23 groups were 33.3% and 51.3%,The detection rates of aminoglycoside modifying enzymes coding genes of aac(3)-Ⅰ,aac(6′)-Ⅰ and ant(3″)-Ⅰ were 64.1%,64.1% and 74.4%,respectively.The others were not found in all 39 isolates tested. CONCLUSIONS The study showed that it is more serious for A.baumannii carrying ?-lactamases and aminoglycoside modifying enzymes coding genes in Shaoxing.
