S-nitrosation:The Prototypic Redox-based Post-translational Modification of Proteins
- VernacularTitle:蛋白质巯基亚硝基化——一种典型氧化还原依赖的蛋白质翻译后修饰
- Author:
Chang CHEN
;
Bo HUANG
;
Peiwei HAN
;
Shaojin DUAN
- Publication Type:Journal Article
- Keywords:
S-nitrosation, nitric oxide, post-translational modification of proteins, redox, signal transduction
- From:
Progress in Biochemistry and Biophysics
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
S-nitrosation, which involves the formation of an S-nitroso function group on a protein cysteine residue, is a prototypic redox-based post-translational modification of proteins, and thereby conveys a large part of the ubiquitous influence of nitric oxide on cellular signal transduction. A purview of this modification was given mainly concerning the characteristics, the detection methods, the functional effects, the relevant diseases and the perspectives.
